October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

Z80 Family history of primary malignant neoplasm

All 16 codes in the Z80 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

16

Can lead a claim

0

Cannot lead a claim

16

What CMS assigns to Z80

None of the 16 codes is assigned a clinical group. None of the 16 is assigned a comorbidity subgroup. None can lead a claim.

Every code in Z80

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
Z80.0Family history of malignant neoplasm of digestive organsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.1Family history of malignant neoplasm of trachea, bronchus and lungCMS: Family history of malig neoplasm of trachea, bronc and lungCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.2Family history of malignant neoplasm of other respiratory and intrathoracic organsCMS: Family hx of malig neoplm of resp and intrathorac organsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.3Family history of malignant neoplasm of breastCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.4 Family history of malignant neoplasm of genital organs
Z80.41Family history of malignant neoplasm of ovaryCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.42Family history of malignant neoplasm of prostateCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.43Family history of malignant neoplasm of testisCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.44Family history of malignant neoplasm of fallopian tube(s)Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.49Family history of malignant neoplasm of other genital organsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.5 Family history of malignant neoplasm of urinary tract
Z80.51Family history of malignant neoplasm of kidneyCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.52Family history of malignant neoplasm of bladderCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.59Family history of malignant neoplasm of other urinary tract organCMS: Family history of malignant neoplasm of urinary tract organCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.6Family history of leukemiaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.7Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissuesCMS: Fam hx of malig neoplm of lymphoid, hematpoetc and rel tissCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.8Family history of malignant neoplasm of other organs or systemsCMS: Family history of malignant neoplasm of organs or systemsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
Z80.9Family history of malignant neoplasm, unspecifiedCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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