ICD-10 · PDGM grouping
Z79 Long term (current) drug therapy
All 32 codes in the Z79 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
ICD-10-CM FY2027 · CMS grouper v07.2.26
Codes in family
32
Can lead a claim
0
Cannot lead a claim
32
What CMS assigns to Z79
None of the 32 codes is assigned a clinical group. None of the 32 is assigned a comorbidity subgroup. None can lead a claim. CMS attaches a code-first note to 3 of the 32.
Code first
CMS grouper convention 176, on Z79.810, Z79.811, Z79.818. Code first:
- , if applicable:
- malignant neoplasm of breast (C50.-)
- malignant neoplasm of prostate (C61)
Every code in Z79
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| Z79.0 Long term (current) use of anticoagulants and antithrombotics/antiplatelets | ||||
| Z79.01 | Long term (current) use of anticoagulants | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
| Z79.02 | Long term (current) use of antithrombotics/antiplatelets | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.1 | Long term (current) use of non-steroidal anti-inflammatories (NSAID)CMS: Long term (current) use of non-steroidal non-inflam (NSAID) | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.2 | Long term (current) use of antibiotics | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.3 | Long term (current) use of hormonal contraceptives | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
| Z79.4 | Long term (current) use of insulin | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
| Z79.5 Long term (current) use of steroids | ||||
| Z79.51 | Long term (current) use of inhaled steroids | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.52 | Long term (current) use of systemic steroids | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.6 Long term (current) use of immunomodulators and immunosuppressants | ||||
| Z79.60 | Long term (current) use of unspecified immunomodulators and immunosuppressantsCMS: Lng trm (crnt) use unsp immunomodulator & immunosuppressant | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.61 | Long term (current) use of immunomodulator | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.62 Long term (current) use of immunosuppressant | ||||
| Z79.620 | Long term (current) use of immunosuppressive biologic | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.621 | Long term (current) use of calcineurin inhibitor | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.622 | Long term (current) use of Janus kinase inhibitor | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.623 | Long term (current) use of mammalian target of rapamycin (mTOR) inhibitorCMS: Long term (crnt) use of mammalian target rapamycin inhibitor | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.624 | Long term (current) use of inhibitors of nucleotide synthesisCMS: Long term (current) use of inhibtr of nucleotide synthesis | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.63 Long term (current) use of chemotherapeutic agent | ||||
| Z79.630 | Long term (current) use of alkylating agent | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.631 | Long term (current) use of antimetabolite agent | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.632 | Long term (current) use of antitumor antibiotic | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.633 | Long term (current) use of mitotic inhibitor | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.634 | Long term (current) use of topoisomerase inhibitor | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.64 | Long term (current) use of myelosuppressive agent | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.69 | Long term (current) use of other immunomodulators and immunosuppressantsCMS: Lng trm (crnt) use of immunomodulator & immunosuppressant | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.8 Other long term (current) drug therapy | ||||
| Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels | ||||
| Z79.810 | Long term (current) use of selective estrogen receptor modulators (SERMs)CMS: Lng trm (crnt) use of slctv estrog receptor modulators | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.811 | Long term (current) use of aromatase inhibitors | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.818 | Long term (current) use of other agents affecting estrogen receptors and estrogen levelsCMS: Lng trm (crnt) use of agnt aff estrog recpt & estrog levels | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.82 | Long term (current) use of aspirin | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
| Z79.83 | Long term (current) use of bisphosphonates | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.84 | Long term (current) use of oral hypoglycemic drugs | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.85 | Long-term (current) use of injectable non-insulin antidiabetic drugsCMS: Lng trm (crnt) use injectable non-insulin antidiabetic drugs | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.89 Other long term (current) drug therapy | ||||
| Z79.890 | Hormone replacement therapy | Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosis | None | None |
| Z79.891 | Long term (current) use of opiate analgesic | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
| Z79.899 | Other long term (current) drug therapy | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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