ICD-10 · PDGM grouping
D80 Immunodeficiency with predominantly antibody defects
All 10 codes in the D80 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
10
Can lead a claim
10
Cannot lead a claim
0
What CMS assigns to D80
All 10 codes group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases. None of the 10 is assigned a comorbidity subgroup. Every code can lead a claim.
Every code in D80
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| D80.0 | Hereditary hypogammaglobulinemia | Can lead a claim | K | None |
| D80.1 | Nonfamilial hypogammaglobulinemia | Can lead a claim | K | None |
| D80.2 | Selective deficiency of immunoglobulin A [IgA] | Can lead a claim | K | None |
| D80.3 | Selective deficiency of immunoglobulin G [IgG] subclasses | Can lead a claim | K | None |
| D80.4 | Selective deficiency of immunoglobulin M [IgM] | Can lead a claim | K | None |
| D80.5 | Immunodeficiency with increased immunoglobulin M [IgM] | Can lead a claim | K | None |
| D80.6 | Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemiaCMS: Antibody defic w near-norm immunoglob or w hyperimmunoglob | Can lead a claim | K | None |
| D80.7 | Transient hypogammaglobulinemia of infancy | Can lead a claim | K | None |
| D80.8 | Other immunodeficiencies with predominantly antibody defects | Can lead a claim | K | None |
| D80.9 | Immunodeficiency with predominantly antibody defects, unspecifiedCMS: Immunodeficiency with predominantly antibody defects, unsp | Can lead a claim | K | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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