October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

Z88 Allergy status to drugs, medicaments and biological substances

All 10 codes in the Z88 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

10

Can lead a claim

0

Cannot lead a claim

10

What CMS assigns to Z88

None of the 10 codes is assigned a clinical group. None of the 10 is assigned a comorbidity subgroup. None can lead a claim.

Every code in Z88

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
Z88.0Allergy status to penicillinCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.1Allergy status to other antibiotic agentsCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.2Allergy status to sulfonamidesCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.3Allergy status to other anti-infective agentsCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.4Allergy status to anesthetic agentCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.5Allergy status to narcotic agentCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.6Allergy status to analgesic agentCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.7Allergy status to serum and vaccineCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.8Allergy status to other drugs, medicaments and biological substancesCMS: Allergy status to other drug/meds/biol substCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z88.9Allergy status to unspecified drugs, medicaments and biological substancesCMS: Allergy status to unspecified drug/meds/biol substCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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