October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

Z29 Encounter for other prophylactic measures

All 8 codes in the Z29 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

8

Can lead a claim

0

Cannot lead a claim

8

What CMS assigns to Z29

None of the 8 codes is assigned a clinical group. None of the 8 is assigned a comorbidity subgroup. None can lead a claim.

Every code in Z29

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
Z29.1 Encounter for prophylactic immunotherapy
Z29.11Encounter for prophylactic immunotherapy for respiratory syncytial virus (RSV)CMS: Enctr for prphylc immther for resp syncytial virus (RSV)Cannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.12Encounter for prophylactic antiveninCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.13Encounter for prophylactic Rho(D) immune globulinCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.14Encounter for prophylactic rabies immune globulinCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.3Encounter for prophylactic fluoride administrationCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.8 Encounter for other specified prophylactic measures
Z29.81Encounter for HIV pre-exposure prophylaxisCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.89Encounter for other specified prophylactic measuresCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
Z29.9Encounter for prophylactic measures, unspecifiedCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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