October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

G92 Toxic encephalopathy

All 8 codes in the G92 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

8

Can lead a claim

0

Cannot lead a claim

8

What CMS assigns to G92

None of the 8 codes is assigned a clinical group. None of the 8 is assigned a comorbidity subgroup. None can lead a claim. CMS attaches a code-first note to all 8.

Code first

CMS grouper convention 13, on G92.8, G92.9. Code first:

  • poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)

CMS grouper convention 43, on G92.00, G92.01, G92.02, G92.03, G92.04, G92.05. Code first:

  • complications of immune effector cellular therapy (T80.82)
  • underlying cause such as:

Every code in G92

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
G92.0 Immune effector cell-associated neurotoxicity syndrome
G92.00Immune effector cell-associated neurotoxicity syndrome, grade unspecifiedCMS: Immune effor cell-associated neurotoxicity synd, grade unspCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.01Immune effector cell-associated neurotoxicity syndrome, grade 1CMS: Immune effector cell-associated neurotoxicity synd, grade 1Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.02Immune effector cell-associated neurotoxicity syndrome, grade 2CMS: Immune effector cell-associated neurotoxicity synd, grade 2Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.03Immune effector cell-associated neurotoxicity syndrome, grade 3CMS: Immune effector cell-associated neurotoxicity synd, grade 3Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.04Immune effector cell-associated neurotoxicity syndrome, grade 4CMS: Immune effector cell-associated neurotoxicity synd, grade 4Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.05Immune effector cell-associated neurotoxicity syndrome, grade 5CMS: Immune effector cell-associated neurotoxicity synd, grade 5Cannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
G92.8Other toxic encephalopathyCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
G92.9Unspecified toxic encephalopathyCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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