ICD-10 · PDGM grouping
E78 Disorders of lipoprotein metabolism and other lipidemias
All 18 codes in the E78 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
18
Can lead a claim
17
Cannot lead a claim
1
What CMS assigns to E78
17 of the 18 codes group to MMTA - Other; 1 is assigned no clinical group. None of the 18 is assigned a comorbidity subgroup. 17 of the 18 can lead a claim.
Every code in E78
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| E78.0 Pure hypercholesterolemia | ||||
| E78.00 | Pure hypercholesterolemia, unspecified | Can lead a claim | A | None |
| E78.01 Familial hypercholesterolemia | ||||
| E78.010 | Homozygous familial hypercholesterolemia [HoFH] | Can lead a claim | A | None |
| E78.011 | Heterozygous familial hypercholesterolemia [HeFH] | Can lead a claim | A | None |
| E78.019 | Familial hypercholesterolemia, unspecified | Can lead a claim | A | None |
| E78.1 | Pure hyperglyceridemia | Can lead a claim | A | None |
| E78.2 | Mixed hyperlipidemia | Can lead a claim | A | None |
| E78.3 | Hyperchylomicronemia | Can lead a claim | A | None |
| E78.4 Other hyperlipidemia | ||||
| E78.41 | Elevated Lipoprotein(a) | Can lead a claim | A | None |
| E78.49 | Other hyperlipidemia | Can lead a claim | A | None |
| E78.5 | Hyperlipidemia, unspecified | Can lead a claim | A | None |
| E78.6 | Lipoprotein deficiency | Can lead a claim | A | None |
| E78.7 Disorders of bile acid and cholesterol metabolism | ||||
| E78.70 | Disorder of bile acid and cholesterol metabolism, unspecifiedCMS: Disorder of bile acid and cholesterol metabolism, unsp | Can lead a claim | A | None |
| E78.71 | Barth syndrome | Can lead a claim | A | None |
| E78.72 | Smith-Lemli-Opitz syndrome | Can lead a claim | A | None |
| E78.79 | Other disorders of bile acid and cholesterol metabolism | Can lead a claim | A | None |
| E78.8 Other disorders of lipoprotein metabolism | ||||
| E78.81 | Lipoid dermatoarthritis | Can lead a claim | A | None |
| E78.89 | Other lipoprotein metabolism disorders | Can lead a claim | A | None |
| E78.9 | Disorder of lipoprotein metabolism, unspecified | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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