ICD-10 · PDGM grouping
D59 Acquired hemolytic anemia
All 16 codes in the D59 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
16
Can lead a claim
16
Cannot lead a claim
0
What CMS assigns to D59
All 16 codes group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases. All 16 count toward the Hemolytic, Aplastic, and Other Anemias comorbidity subgroup. Every code can lead a claim. CMS attaches a code-first note to 1 of the 16.
- Hemolytic, Aplastic, and Other Anemias: can award the low comorbidity tier as a secondary diagnosis.
Code first
CMS grouper convention 7, on D59.39. Code first:
- , if applicable, any associated:
- COVID-19 (U07.1)
- complications of heart transplant (T86.2-)
- complications of kidney transplant (T86.1-)
- complications of liver transplant (T86.4-)
Every code in D59
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| D59.0 | Drug-induced autoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.1 Other autoimmune hemolytic anemias | ||||
| D59.10 | Autoimmune hemolytic anemia, unspecified | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.11 | Warm autoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.12 | Cold autoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.13 | Mixed type autoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.19 | Other autoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.2 | Drug-induced nonautoimmune hemolytic anemia | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.3 Hemolytic-uremic syndrome | ||||
| D59.30 | Hemolytic-uremic syndrome, unspecified | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.31 | Infection-associated hemolytic-uremic syndrome | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.32 | Hereditary hemolytic-uremic syndrome | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.39 | Other hemolytic-uremic syndrome | Can lead a claim, code first applies | K | Hemolytic, Aplastic, and Other Anemias |
| D59.4 | Other nonautoimmune hemolytic anemias | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.5 | Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.6 | Hemoglobinuria due to hemolysis from other external causes | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.8 | Other acquired hemolytic anemias | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
| D59.9 | Acquired hemolytic anemia, unspecified | Can lead a claim | K | Hemolytic, Aplastic, and Other Anemias |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
The monthly home health regs digest
What CMS changed, what's due next, and what to do about it — one email a month, no fluff. Read the first issue