ICD-10 · PDGM grouping

D55-D59 — Hemolytic anemias

Every ICD-10-CM code in this range and the PDGM clinical group CMS assigns to it, read from the CMS grouper crosswalk v07.1.26.

OASIS-E2 v1.00.0 · ingested 2026-04-26

Codes in range

No clinical group

A period cannot be grouped from these.

Barred as primary

CMS rejects these in the primary position.

Where these codes group

72 of the 79 codes in D55-D59 group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases, but the range is not uniform — it spreads across 2 clinical groups. A further 1 are assigned no clinical group at all, which means a 30-day period cannot be grouped from them.

Every code in D55-D59

Descriptions are CMS’s own, abbreviated as CMS abbreviates them.

Code	Description	Clinical group	Primary position
D550	Anemia due to glucose-6-phosphate dehydrogenase deficiency	K	Accepted
D551	Anemia due to other disorders of glutathione metabolism	K	Accepted
D5521	Anemia due to pyruvate kinase deficiency	K	Accepted
D5529	Anemia due to other disorders of glycolytic enzymes	K	Accepted
D553	Anemia due to disorders of nucleotide metabolism	K	Accepted
D558	Other anemias due to enzyme disorders	K	Accepted
D559	Anemia due to enzyme disorder, unspecified	K	Accepted
D560	Alpha thalassemia	K	Accepted
D561	Beta thalassemia	K	Accepted
D562	Delta-beta thalassemia	K	Accepted
D563	Thalassemia minor	K	Accepted
D564	Hereditary persistence of fetal hemoglobin [HPFH]	K	Accepted
D565	Hemoglobin E-beta thalassemia	K	Accepted
D568	Other thalassemias	K	Accepted
D569	Thalassemia, unspecified	K	Accepted
D5700	Hb-SS disease with crisis, unspecified	K	Accepted
D5701	Hb-SS disease with acute chest syndrome	K	Accepted
D5702	Hb-SS disease with splenic sequestration	K	Accepted
D5703	Hb-SS disease with cerebral vascular involvement	B	Accepted
D5704	Hb-SS disease with dactylitis	K	Accepted
D5709	Hb-SS disease with crisis with other specified complication	K	Accepted
D571	Sickle-cell disease without crisis	K	Accepted
D5720	Sickle-cell/Hb-C disease without crisis	K	Accepted
D57211	Sickle-cell/Hb-C disease with acute chest syndrome	K	Accepted
D57212	Sickle-cell/Hb-C disease with splenic sequestration	K	Accepted
D57213	Sickle-cell/Hb-C disease with cerebral vascular involvement	B	Accepted
D57214	Sickle-cell/Hb-C disease with dactylitis	K	Accepted
D57218	Sickle-cell/Hb-C disease with crisis with oth complication	K	Accepted
D57219	Sickle-cell/Hb-C disease with crisis, unspecified	K	Accepted
D573	Sickle-cell trait	None	Cannot group
D5740	Sickle-cell thalassemia without crisis	K	Accepted
D57411	Sickle-cell thalassemia, unsp, with acute chest syndrome	K	Accepted
D57412	Sickle-cell thalassemia, unsp, with splenic sequestration	K	Accepted
D57413	Sickle-cell thalassemia, unsp, with cerebral vascular invl	B	Accepted
D57414	Sickle-cell thalassemia, unspecified, with dactylitis	K	Accepted
D57418	Sickle-cell thalassemia, unsp, with crisis with oth comp	K	Accepted
D57419	Sickle-cell thalassemia, unspecified, with crisis	K	Accepted
D5742	Sickle-cell thalassemia beta zero without crisis	K	Accepted
D57431	Sickle-cell thalassemia beta zero with acute chest syndrome	K	Accepted
D57432	Sickle-cell thalassemia beta zero with splenic sequestration	K	Accepted
D57433	Sickle-cell thalassemia beta zero with cereb vascular invl	B	Accepted
D57434	Sickle-cell thalassemia beta zero with dactylitis	K	Accepted
D57438	Sickle-cell thalassemia beta zero with crisis with oth comp	K	Accepted
D57439	Sickle-cell thalassemia beta zero with crisis, unspecified	K	Accepted
D5744	Sickle-cell thalassemia beta plus without crisis	K	Accepted
D57451	Sickle-cell thalassemia beta plus with acute chest syndrome	K	Accepted
D57452	Sickle-cell thalassemia beta plus with splenic sequestration	K	Accepted
D57453	Sickle-cell thalassemia beta plus with cereb vascular invl	B	Accepted
D57454	Sickle-cell thalassemia beta plus with dactylitis	K	Accepted
D57458	Sickle-cell thalassemia beta plus with crisis with oth comp	K	Accepted
D57459	Sickle-cell thalassemia beta plus with crisis, unspecified	K	Accepted
D5780	Other sickle-cell disorders without crisis	K	Accepted
D57811	Other sickle-cell disorders with acute chest syndrome	K	Accepted
D57812	Other sickle-cell disorders with splenic sequestration	K	Accepted
D57813	Other sickle-cell disorders with cerebral vascular invl	B	Accepted
D57814	Other sickle-cell disorders with dactylitis	K	Accepted
D57818	Other sickle-cell disorders with crisis with oth comp	K	Accepted
D57819	Other sickle-cell disorders with crisis, unspecified	K	Accepted
D580	Hereditary spherocytosis	K	Accepted
D581	Hereditary elliptocytosis	K	Accepted
D582	Other hemoglobinopathies	K	Accepted
D588	Other specified hereditary hemolytic anemias	K	Accepted
D589	Hereditary hemolytic anemia, unspecified	K	Accepted
D590	Drug-induced autoimmune hemolytic anemia	K	Accepted
D5910	Autoimmune hemolytic anemia, unspecified	K	Accepted
D5911	Warm autoimmune hemolytic anemia	K	Accepted
D5912	Cold autoimmune hemolytic anemia	K	Accepted
D5913	Mixed type autoimmune hemolytic anemia	K	Accepted
D5919	Other autoimmune hemolytic anemia	K	Accepted
D592	Drug-induced nonautoimmune hemolytic anemia	K	Accepted
D5930	Hemolytic-uremic syndrome, unspecified	K	Accepted
D5931	Infection-associated hemolytic-uremic syndrome	K	Accepted
D5932	Hereditary hemolytic-uremic syndrome	K	Accepted
D5939	Other hemolytic-uremic syndrome	K	Accepted
D594	Other nonautoimmune hemolytic anemias	K	Accepted
D595	Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]	K	Accepted
D596	Hemoglobinuria due to hemolysis from other external causes	K	Accepted
D598	Other acquired hemolytic anemias	K	Accepted
D599	Acquired hemolytic anemia, unspecified	K	Accepted

Source: CMS HH PPS Grouper Software v07.1.26, effective 2026-04-01. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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D55-D59 — Hemolytic anemias

Where these codes group

Every code in D55-D59

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