October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas

All 12 codes in the C88 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

12

Can lead a claim

12

Cannot lead a claim

0

What CMS assigns to C88

All 12 codes group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases. Comorbidity subgroups: 10 toward Follicular and Other Non-Hodgkin’s Lymphoma, and Leukemia; 2 toward Non-Hodgkin’s Lymphoma. Every code can lead a claim.

  • Follicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
  • Non-Hodgkin’s Lymphoma

Every code in C88

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
C88.0 Waldenstrom macroglobulinemia
C88.00Waldenstrom macroglobulinemia not having achieved remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.01Waldenstrom macroglobulinemia, in remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.2 Heavy chain disease
C88.20Heavy chain disease not having achieved remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.21Heavy chain disease, in remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.3 Immunoproliferative small intestinal disease
C88.30Immunoproliferative small intestinal disease not having achieved remissionCMS: Immunoproliferative small intestinal disease not remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.31Immunoproliferative small intestinal disease, in remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
C88.40Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] not having achieved remissionCMS: Extrnod mrgnl B-cell lymph mucosa-assoc lym tiss not remisCan lead a claimKNon-Hodgkin’s Lymphoma
C88.41Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma], in remissionCMS: Extrnod mrgnl B-cell lymph mucosa-assoc lym tiss, in remisCan lead a claimKNon-Hodgkin’s Lymphoma
C88.8 Other malignant immunoproliferative diseases
C88.80Other malignant immunoproliferative diseases not having achieved remissionCMS: Other malignant immunoproliferative diseases not remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.81Other malignant immunoproliferative diseases, in remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.9 Malignant immunoproliferative disease, unspecified
C88.90Malignant immunoproliferative disease, unspecified not having achieved remissionCMS: Malignant immunoproliferative disease, unsp not remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia
C88.91Malignant immunoproliferative disease, unspecified, in remissionCMS: Malignant immunoproliferative disease, unsp, in remissionCan lead a claimKFollicular and Other Non-Hodgkin’s Lymphoma, and Leukemia

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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