ICD-10 · PDGM grouping
C45 Mesothelioma
All 5 codes in the C45 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
5
Can lead a claim
4
Cannot lead a claim
1
What CMS assigns to C45
4 of the 5 codes group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases; 1 is assigned no clinical group. Comorbidity subgroups: 2 toward Malignant Neoplasm of Trachea, Bronchus, Lung, and Mediastinum; 1 toward Malignant Neoplasm of Pancreas, Peritoneum and Retroperitoneum; 2 are assigned none. 4 of the 5 can lead a claim.
- Malignant Neoplasm of Trachea, Bronchus, Lung, and Mediastinum: can award the low comorbidity tier as a secondary diagnosis.
- Malignant Neoplasm of Pancreas, Peritoneum and Retroperitoneum
Every code in C45
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| C45.0 | Mesothelioma of pleura | Can lead a claim | K | Malignant Neoplasm of Trachea, Bronchus, Lung, and Mediastinum |
| C45.1 | Mesothelioma of peritoneum | Can lead a claim | K | Malignant Neoplasm of Pancreas, Peritoneum and Retroperitoneum |
| C45.2 | Mesothelioma of pericardium | Can lead a claim | K | Malignant Neoplasm of Trachea, Bronchus, Lung, and Mediastinum |
| C45.7 | Mesothelioma of other sites | Can lead a claim | K | None |
| C45.9 | Mesothelioma, unspecified | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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