October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

D49-D49 — Neoplasms of unspecified behavior

Every ICD-10-CM code in this range and the PDGM clinical group CMS assigns to it, read from the CMS grouper crosswalk v07.2.26.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in range

14

No clinical group

2

A period cannot be grouped from these.

Barred as primary

0

CMS rejects these in the primary position.

Where these codes group

10 of the 14 codes in D49-D49 group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases, but the range is not uniform — it spreads across 2 clinical groups. A further 2 are assigned no clinical group at all, which means a 30-day period cannot be grouped from them.

Code families in D49-D49

One page per three-character family: every code in it, whether it can lead a claim, its clinical group and comorbidity subgroup.

Every code in D49-D49

Descriptions are CMS’s own, abbreviated as CMS abbreviates them.

CodeDescriptionClinical groupPrimary position
D490Neoplasm of unspecified behavior of digestive systemKCan lead a claim
D491Neoplasm of unspecified behavior of respiratory systemKCan lead a claim
D492Neoplasm of unsp behavior of bone, soft tissue, and skinKCan lead a claim
D493Neoplasm of unspecified behavior of breastKCan lead a claim
D494Neoplasm of unspecified behavior of bladderKCan lead a claim
D49511Neoplasm of unspecified behavior of right kidneyKCan lead a claim
D49512Neoplasm of unspecified behavior of left kidneyKCan lead a claim
D49519Neoplasm of unspecified behavior of unspecified kidneyNoneCannot lead a claim
D4959Neoplasm of unspecified behavior of other GU organKCan lead a claim
D496Neoplasm of unspecified behavior of brainBCan lead a claim
D497Neoplm of unsp behav of endo glands and oth prt nervous sysKCan lead a claim
D4981Neoplasm of unspecified behavior of retina and choroidBCan lead a claim
D4989Neoplasm of unspecified behavior of other specified sitesKCan lead a claim
D499Neoplasm of unspecified behavior of unspecified siteNoneCannot lead a claim

Source: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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