October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

Y64 Contaminated medical or biological substances

All 4 codes in the Y64 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

4

Can lead a claim

0

Cannot lead a claim

4

What CMS assigns to Y64

None of the 4 codes is assigned a clinical group. None of the 4 is assigned a comorbidity subgroup. None can lead a claim.

Every code in Y64

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
Y64.0Contaminated medical or biological substance, transfused or infusedCMS: Contaminated med/biolog sub, transfused or infusedCannot lead a claimExternal cause of injury code not reportable as principal diagnosisNoneNone
Y64.1Contaminated medical or biological substance, injected or used for immunizationCMS: Contaminated med/biolog sub, injected or used for immunizCannot lead a claimExternal cause of injury code not reportable as principal diagnosisNoneNone
Y64.8Contaminated medical or biological substance administered by other meansCMS: Contaminated med/biolog sub administered by oth meansCannot lead a claimExternal cause of injury code not reportable as principal diagnosisNoneNone
Y64.9Contaminated medical or biological substance administered by unspecified meansCMS: Contaminated med/biolog sub administered by unsp meansCannot lead a claimExternal cause of injury code not reportable as principal diagnosisNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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