October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

T49 Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs

All 180 codes in the T49 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

180

Can lead a claim

120

Cannot lead a claim

60

What CMS assigns to T49

120 of the 180 codes group to MMTA - Other; 60 are assigned no clinical group. None of the 180 is assigned a comorbidity subgroup. 120 of the 180 can lead a claim.

Every code in T49

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
T49.0 Poisoning by, adverse effect of and underdosing of local antifungal, anti-infective and anti-inflammatory drugs
T49.0X Poisoning by, adverse effect of and underdosing of local antifungal, anti-infective and anti-inflammatory drugs
T49.0X1 Poisoning by local antifungal, anti-infective and anti-inflammatory drugs, accidental (unintentional)
T49.0X1APoisoning by local antifungal, anti-infective and anti-inflammatory drugs, accidental (unintentional), initial encounterCMS: Poisoning by local antifung/infect/inflamm drugs, acc, initCan lead a claimANone
T49.0X1DPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, accidental (unintentional), subsequent encounterCMS: Poisoning by local antifung/infect/inflamm drugs, acc, subsCan lead a claimANone
T49.0X1SPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, accidental (unintentional), sequelaCMS: Poisn by local antifung/infect/inflamm drugs, acc, sequelaCan lead a claimANone
T49.0X2 Poisoning by local antifungal, anti-infective and anti-inflammatory drugs, intentional self-harm
T49.0X2APoisoning by local antifungal, anti-infective and anti-inflammatory drugs, intentional self-harm, initial encounterCMS: Poisn by local antifung/infect/inflamm drugs, slf-hrm, initCan lead a claimANone
T49.0X2DPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, intentional self-harm, subsequent encounterCMS: Poisn by local antifung/infect/inflamm drugs, slf-hrm, subsCan lead a claimANone
T49.0X2SPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, intentional self-harm, sequelaCMS: Poisn by local antifung/infect/inflamm drugs, slf-hrm, sqlaCan lead a claimANone
T49.0X3 Poisoning by local antifungal, anti-infective and anti-inflammatory drugs, assault
T49.0X3APoisoning by local antifungal, anti-infective and anti-inflammatory drugs, assault, initial encounterCMS: Poisn by local antifung/infect/inflamm drugs, assault, initCan lead a claimANone
T49.0X3DPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, assault, subsequent encounterCMS: Poisn by local antifung/infect/inflamm drugs, assault, subsCan lead a claimANone
T49.0X3SPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, assault, sequelaCMS: Poisn by local antifung/infect/inflamm drugs, asslt, sequelaCan lead a claimANone
T49.0X4 Poisoning by local antifungal, anti-infective and anti-inflammatory drugs, undetermined
T49.0X4APoisoning by local antifungal, anti-infective and anti-inflammatory drugs, undetermined, initial encounterCMS: Poisn by local antifung/infect/inflamm drugs, undet, initCan lead a claimANone
T49.0X4DPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, undetermined, subsequent encounterCMS: Poisn by local antifung/infect/inflamm drugs, undet, subsCan lead a claimANone
T49.0X4SPoisoning by local antifungal, anti-infective and anti-inflammatory drugs, undetermined, sequelaCMS: Poisn by local antifung/infect/inflamm drugs, undet, sequelaCan lead a claimANone
T49.0X5 Adverse effect of local antifungal, anti-infective and anti-inflammatory drugs
T49.0X5AAdverse effect of local antifungal, anti-infective and anti-inflammatory drugs, initial encounterCMS: Adverse effect of local antifung/infect/inflamm drugs, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.0X5DAdverse effect of local antifungal, anti-infective and anti-inflammatory drugs, subsequent encounterCMS: Adverse effect of local antifung/infect/inflamm drugs, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.0X5SAdverse effect of local antifungal, anti-infective and anti-inflammatory drugs, sequelaCMS: Advrs effect of local antifung/infect/inflamm drugs, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.0X6 Underdosing of local antifungal, anti-infective and anti-inflammatory drugs
T49.0X6AUnderdosing of local antifungal, anti-infective and anti-inflammatory drugs, initial encounterCMS: Underdosing of local antifung/infect/inflamm drugs, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.0X6DUnderdosing of local antifungal, anti-infective and anti-inflammatory drugs, subsequent encounterCMS: Underdosing of local antifung/infect/inflamm drugs, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.0X6SUnderdosing of local antifungal, anti-infective and anti-inflammatory drugs, sequelaCMS: Underdosing of local antifung/infect/inflamm drugs, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1 Poisoning by, adverse effect of and underdosing of antipruritics
T49.1X Poisoning by, adverse effect of and underdosing of antipruritics
T49.1X1 Poisoning by antipruritics, accidental (unintentional)
T49.1X1APoisoning by antipruritics, accidental (unintentional), initial encounterCMS: Poisoning by antipruritics, accidental (unintentional), initCan lead a claimANone
T49.1X1DPoisoning by antipruritics, accidental (unintentional), subsequent encounterCMS: Poisoning by antipruritics, accidental (unintentional), subsCan lead a claimANone
T49.1X1SPoisoning by antipruritics, accidental (unintentional), sequelaCMS: Poisoning by antipruritics, accidental, sequelaCan lead a claimANone
T49.1X2 Poisoning by antipruritics, intentional self-harm
T49.1X2APoisoning by antipruritics, intentional self-harm, initial encounterCMS: Poisoning by antipruritics, intentional self-harm, initCan lead a claimANone
T49.1X2DPoisoning by antipruritics, intentional self-harm, subsequent encounterCMS: Poisoning by antipruritics, intentional self-harm, subsCan lead a claimANone
T49.1X2SPoisoning by antipruritics, intentional self-harm, sequelaCan lead a claimANone
T49.1X3 Poisoning by antipruritics, assault
T49.1X3APoisoning by antipruritics, assault, initial encounterCan lead a claimANone
T49.1X3DPoisoning by antipruritics, assault, subsequent encounterCan lead a claimANone
T49.1X3SPoisoning by antipruritics, assault, sequelaCan lead a claimANone
T49.1X4 Poisoning by antipruritics, undetermined
T49.1X4APoisoning by antipruritics, undetermined, initial encounterCan lead a claimANone
T49.1X4DPoisoning by antipruritics, undetermined, subsequent encounterCMS: Poisoning by antipruritics, undetermined, subs encntrCan lead a claimANone
T49.1X4SPoisoning by antipruritics, undetermined, sequelaCan lead a claimANone
T49.1X5 Adverse effect of antipruritics
T49.1X5AAdverse effect of antipruritics, initial encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1X5DAdverse effect of antipruritics, subsequent encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1X5SAdverse effect of antipruritics, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1X6 Underdosing of antipruritics
T49.1X6AUnderdosing of antipruritics, initial encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1X6DUnderdosing of antipruritics, subsequent encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.1X6SUnderdosing of antipruritics, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2 Poisoning by, adverse effect of and underdosing of local astringents and local detergents
T49.2X Poisoning by, adverse effect of and underdosing of local astringents and local detergents
T49.2X1 Poisoning by local astringents and local detergents, accidental (unintentional)
T49.2X1APoisoning by local astringents and local detergents, accidental (unintentional), initial encounterCMS: Poisoning by local astringents/detergents, accidental, initCan lead a claimANone
T49.2X1DPoisoning by local astringents and local detergents, accidental (unintentional), subsequent encounterCMS: Poisoning by local astringents/detergents, accidental, subsCan lead a claimANone
T49.2X1SPoisoning by local astringents and local detergents, accidental (unintentional), sequelaCMS: Poisoning by local astringents/detergents, acc, sequelaCan lead a claimANone
T49.2X2 Poisoning by local astringents and local detergents, intentional self-harm
T49.2X2APoisoning by local astringents and local detergents, intentional self-harm, initial encounterCMS: Poisoning by local astringents/detergents, self-harm, initCan lead a claimANone
T49.2X2DPoisoning by local astringents and local detergents, intentional self-harm, subsequent encounterCMS: Poisoning by local astringents/detergents, self-harm, subsCan lead a claimANone
T49.2X2SPoisoning by local astringents and local detergents, intentional self-harm, sequelaCMS: Poisn by local astringents/detergents, self-harm, sequelaCan lead a claimANone
T49.2X3 Poisoning by local astringents and local detergents, assault
T49.2X3APoisoning by local astringents and local detergents, assault, initial encounterCMS: Poisoning by local astringents/detergents, assault, initCan lead a claimANone
T49.2X3DPoisoning by local astringents and local detergents, assault, subsequent encounterCMS: Poisoning by local astringents/detergents, assault, subsCan lead a claimANone
T49.2X3SPoisoning by local astringents and local detergents, assault, sequelaCMS: Poisoning by local astringents/detergents, assault, sequelaCan lead a claimANone
T49.2X4 Poisoning by local astringents and local detergents, undetermined
T49.2X4APoisoning by local astringents and local detergents, undetermined, initial encounterCMS: Poisoning by local astringents/detergents, undet, initCan lead a claimANone
T49.2X4DPoisoning by local astringents and local detergents, undetermined, subsequent encounterCMS: Poisoning by local astringents/detergents, undet, subsCan lead a claimANone
T49.2X4SPoisoning by local astringents and local detergents, undetermined, sequelaCMS: Poisoning by local astringents/detergents, undet, sequelaCan lead a claimANone
T49.2X5 Adverse effect of local astringents and local detergents
T49.2X5AAdverse effect of local astringents and local detergents, initial encounterCMS: Adverse effect of local astringents/detergents, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2X5DAdverse effect of local astringents and local detergents, subsequent encounterCMS: Adverse effect of local astringents/detergents, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2X5SAdverse effect of local astringents and local detergents, sequelaCMS: Adverse effect of local astringents/detergents, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2X6 Underdosing of local astringents and local detergents
T49.2X6AUnderdosing of local astringents and local detergents, initial encounterCMS: Underdosing of local astringents and local detergents, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2X6DUnderdosing of local astringents and local detergents, subsequent encounterCMS: Underdosing of local astringents and local detergents, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.2X6SUnderdosing of local astringents and local detergents, sequelaCMS: Underdosing of local astringents/detergents, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3 Poisoning by, adverse effect of and underdosing of emollients, demulcents and protectants
T49.3X Poisoning by, adverse effect of and underdosing of emollients, demulcents and protectants
T49.3X1 Poisoning by emollients, demulcents and protectants, accidental (unintentional)
T49.3X1APoisoning by emollients, demulcents and protectants, accidental (unintentional), initial encounterCMS: Poisoning by emollients, demulcents and protect, acc, initCan lead a claimANone
T49.3X1DPoisoning by emollients, demulcents and protectants, accidental (unintentional), subsequent encounterCMS: Poisoning by emollients, demulcents and protect, acc, subsCan lead a claimANone
T49.3X1SPoisoning by emollients, demulcents and protectants, accidental (unintentional), sequelaCMS: Poisn by emollients, demulcents and protect, acc, sequelaCan lead a claimANone
T49.3X2 Poisoning by emollients, demulcents and protectants, intentional self-harm
T49.3X2APoisoning by emollients, demulcents and protectants, intentional self-harm, initial encounterCMS: Poisn by emollients, demulcents and protect, self-harm, initCan lead a claimANone
T49.3X2DPoisoning by emollients, demulcents and protectants, intentional self-harm, subsequent encounterCMS: Poisn by emollients, demulcents and protect, self-harm, subsCan lead a claimANone
T49.3X2SPoisoning by emollients, demulcents and protectants, intentional self-harm, sequelaCMS: Poisn by emollients, demulcents and protect, slf-hrm, sqlaCan lead a claimANone
T49.3X3 Poisoning by emollients, demulcents and protectants, assault
T49.3X3APoisoning by emollients, demulcents and protectants, assault, initial encounterCMS: Poisn by emollients, demulcents and protect, assault, initCan lead a claimANone
T49.3X3DPoisoning by emollients, demulcents and protectants, assault, subsequent encounterCMS: Poisn by emollients, demulcents and protect, assault, subsCan lead a claimANone
T49.3X3SPoisoning by emollients, demulcents and protectants, assault, sequelaCMS: Poisn by emollients, demulcents and protect, asslt, sequelaCan lead a claimANone
T49.3X4 Poisoning by emollients, demulcents and protectants, undetermined
T49.3X4APoisoning by emollients, demulcents and protectants, undetermined, initial encounterCMS: Poisoning by emollients, demulcents and protect, undet, initCan lead a claimANone
T49.3X4DPoisoning by emollients, demulcents and protectants, undetermined, subsequent encounterCMS: Poisoning by emollients, demulcents and protect, undet, subsCan lead a claimANone
T49.3X4SPoisoning by emollients, demulcents and protectants, undetermined, sequelaCMS: Poisn by emollients, demulcents and protect, undet, sequelaCan lead a claimANone
T49.3X5 Adverse effect of emollients, demulcents and protectants
T49.3X5AAdverse effect of emollients, demulcents and protectants, initial encounterCMS: Adverse effect of emollients, demulcents and protect, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3X5DAdverse effect of emollients, demulcents and protectants, subsequent encounterCMS: Adverse effect of emollients, demulcents and protect, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3X5SAdverse effect of emollients, demulcents and protectants, sequelaCMS: Advrs effect of emollients, demulcents and protect, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3X6 Underdosing of emollients, demulcents and protectants
T49.3X6AUnderdosing of emollients, demulcents and protectants, initial encounterCMS: Underdosing of emollients, demulcents and protectants, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3X6DUnderdosing of emollients, demulcents and protectants, subsequent encounterCMS: Underdosing of emollients, demulcents and protectants, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.3X6SUnderdosing of emollients, demulcents and protectants, sequelaCMS: Underdosing of emollients, demulcents and protect, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4 Poisoning by, adverse effect of and underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations
T49.4X Poisoning by, adverse effect of and underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations
T49.4X1 Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, accidental (unintentional)
T49.4X1APoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, accidental (unintentional), initial encounterCMS: Poisoning by keratolyt/keratplst/hair trmt drug, acc, initCan lead a claimANone
T49.4X1DPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, accidental (unintentional), subsequent encounterCMS: Poisoning by keratolyt/keratplst/hair trmt drug, acc, subsCan lead a claimANone
T49.4X1SPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, accidental (unintentional), sequelaCMS: Poisn by keratolyt/keratplst/hair trmt drug, acc, sequelaCan lead a claimANone
T49.4X2 Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, intentional self-harm
T49.4X2APoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, intentional self-harm, initial encounterCMS: Poisn by keratolyt/keratplst/hair trmt drug, self-harm, initCan lead a claimANone
T49.4X2DPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, intentional self-harm, subsequent encounterCMS: Poisn by keratolyt/keratplst/hair trmt drug, self-harm, subsCan lead a claimANone
T49.4X2SPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, intentional self-harm, sequelaCMS: Poisn by keratolyt/keratplst/hair trmt drug, slf-hrm, sqlaCan lead a claimANone
T49.4X3 Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, assault
T49.4X3APoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, assault, initial encounterCMS: Poisn by keratolyt/keratplst/hair trmt drug, assault, initCan lead a claimANone
T49.4X3DPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, assault, subsequent encounterCMS: Poisn by keratolyt/keratplst/hair trmt drug, assault, subsCan lead a claimANone
T49.4X3SPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, assault, sequelaCMS: Poisn by keratolyt/keratplst/hair trmt drug, asslt, sequelaCan lead a claimANone
T49.4X4 Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined
T49.4X4APoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, initial encounterCMS: Poisoning by keratolyt/keratplst/hair trmt drug, undet, initCan lead a claimANone
T49.4X4DPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, subsequent encounterCMS: Poisoning by keratolyt/keratplst/hair trmt drug, undet, subsCan lead a claimANone
T49.4X4SPoisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, sequelaCMS: Poisn by keratolyt/keratplst/hair trmt drug, undet, sequelaCan lead a claimANone
T49.4X5 Adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations
T49.4X5AAdverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounterCMS: Adverse effect of keratolyt/keratplst/hair trmt drug, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4X5DAdverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations, subsequent encounterCMS: Adverse effect of keratolyt/keratplst/hair trmt drug, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4X5SAdverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations, sequelaCMS: Advrs effect of keratolyt/keratplst/hair trmt drug, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4X6 Underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations
T49.4X6AUnderdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounterCMS: Underdosing of keratolyt/keratplst/hair trmt drug, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4X6DUnderdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, subsequent encounterCMS: Underdosing of keratolyt/keratplst/hair trmt drug, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.4X6SUnderdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, sequelaCMS: Underdosing of keratolyt/keratplst/hair trmt drug, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5 Poisoning by, adverse effect of and underdosing of ophthalmological drugs and preparations
T49.5X Poisoning by, adverse effect of and underdosing of ophthalmological drugs and preparations
T49.5X1 Poisoning by ophthalmological drugs and preparations, accidental (unintentional)
T49.5X1APoisoning by ophthalmological drugs and preparations, accidental (unintentional), initial encounterCMS: Poisoning by opth drugs and preparations, accidental, initCan lead a claimANone
T49.5X1DPoisoning by ophthalmological drugs and preparations, accidental (unintentional), subsequent encounterCMS: Poisoning by opth drugs and preparations, accidental, subsCan lead a claimANone
T49.5X1SPoisoning by ophthalmological drugs and preparations, accidental (unintentional), sequelaCMS: Poisoning by opth drugs and prep, accidental, sequelaCan lead a claimANone
T49.5X2 Poisoning by ophthalmological drugs and preparations, intentional self-harm
T49.5X2APoisoning by ophthalmological drugs and preparations, intentional self-harm, initial encounterCMS: Poisoning by opth drugs and preparations, self-harm, initCan lead a claimANone
T49.5X2DPoisoning by ophthalmological drugs and preparations, intentional self-harm, subsequent encounterCMS: Poisoning by opth drugs and preparations, self-harm, subsCan lead a claimANone
T49.5X2SPoisoning by ophthalmological drugs and preparations, intentional self-harm, sequelaCMS: Poisoning by opth drugs and preparations, self-harm, sequelaCan lead a claimANone
T49.5X3 Poisoning by ophthalmological drugs and preparations, assault
T49.5X3APoisoning by ophthalmological drugs and preparations, assault, initial encounterCMS: Poisoning by opth drugs and preparations, assault, initCan lead a claimANone
T49.5X3DPoisoning by ophthalmological drugs and preparations, assault, subsequent encounterCMS: Poisoning by opth drugs and preparations, assault, subsCan lead a claimANone
T49.5X3SPoisoning by ophthalmological drugs and preparations, assault, sequelaCMS: Poisoning by opth drugs and preparations, assault, sequelaCan lead a claimANone
T49.5X4 Poisoning by ophthalmological drugs and preparations, undetermined
T49.5X4APoisoning by ophthalmological drugs and preparations, undetermined, initial encounterCMS: Poisoning by opth drugs and preparations, undetermined, initCan lead a claimANone
T49.5X4DPoisoning by ophthalmological drugs and preparations, undetermined, subsequent encounterCMS: Poisoning by opth drugs and preparations, undetermined, subsCan lead a claimANone
T49.5X4SPoisoning by ophthalmological drugs and preparations, undetermined, sequelaCMS: Poisoning by opth drugs and prep, undetermined, sequelaCan lead a claimANone
T49.5X5 Adverse effect of ophthalmological drugs and preparations
T49.5X5AAdverse effect of ophthalmological drugs and preparations, initial encounterCMS: Adverse effect of opth drugs and preparations, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5X5DAdverse effect of ophthalmological drugs and preparations, subsequent encounterCMS: Adverse effect of opth drugs and preparations, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5X5SAdverse effect of ophthalmological drugs and preparations, sequelaCMS: Adverse effect of opth drugs and preparations, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5X6 Underdosing of ophthalmological drugs and preparations
T49.5X6AUnderdosing of ophthalmological drugs and preparations, initial encounterCMS: Underdosing of ophthalmological drugs and preparations, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5X6DUnderdosing of ophthalmological drugs and preparations, subsequent encounterCMS: Underdosing of ophthalmological drugs and preparations, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.5X6SUnderdosing of ophthalmological drugs and preparations, sequelaCMS: Underdosing of opth drugs and preparations, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6 Poisoning by, adverse effect of and underdosing of otorhinolaryngological drugs and preparations
T49.6X Poisoning by, adverse effect of and underdosing of otorhinolaryngological drugs and preparations
T49.6X1 Poisoning by otorhinolaryngological drugs and preparations, accidental (unintentional)
T49.6X1APoisoning by otorhinolaryngological drugs and preparations, accidental (unintentional), initial encounterCMS: Poisoning by otorhino drugs and prep, accidental, initCan lead a claimANone
T49.6X1DPoisoning by otorhinolaryngological drugs and preparations, accidental (unintentional), subsequent encounterCMS: Poisoning by otorhino drugs and prep, accidental, subsCan lead a claimANone
T49.6X1SPoisoning by otorhinolaryngological drugs and preparations, accidental (unintentional), sequelaCMS: Poisoning by otorhino drugs and prep, accidental, sequelaCan lead a claimANone
T49.6X2 Poisoning by otorhinolaryngological drugs and preparations, intentional self-harm
T49.6X2APoisoning by otorhinolaryngological drugs and preparations, intentional self-harm, initial encounterCMS: Poisoning by otorhino drugs and prep, self-harm, initCan lead a claimANone
T49.6X2DPoisoning by otorhinolaryngological drugs and preparations, intentional self-harm, subsequent encounterCMS: Poisoning by otorhino drugs and prep, self-harm, subsCan lead a claimANone
T49.6X2SPoisoning by otorhinolaryngological drugs and preparations, intentional self-harm, sequelaCMS: Poisoning by otorhino drugs and prep, self-harm, sequelaCan lead a claimANone
T49.6X3 Poisoning by otorhinolaryngological drugs and preparations, assault
T49.6X3APoisoning by otorhinolaryngological drugs and preparations, assault, initial encounterCMS: Poisoning by otorhino drugs and preparations, assault, initCan lead a claimANone
T49.6X3DPoisoning by otorhinolaryngological drugs and preparations, assault, subsequent encounterCMS: Poisoning by otorhino drugs and preparations, assault, subsCan lead a claimANone
T49.6X3SPoisoning by otorhinolaryngological drugs and preparations, assault, sequelaCMS: Poisoning by otorhino drugs and prep, assault, sequelaCan lead a claimANone
T49.6X4 Poisoning by otorhinolaryngological drugs and preparations, undetermined
T49.6X4APoisoning by otorhinolaryngological drugs and preparations, undetermined, initial encounterCMS: Poisoning by otorhino drugs and prep, undetermined, initCan lead a claimANone
T49.6X4DPoisoning by otorhinolaryngological drugs and preparations, undetermined, subsequent encounterCMS: Poisoning by otorhino drugs and prep, undetermined, subsCan lead a claimANone
T49.6X4SPoisoning by otorhinolaryngological drugs and preparations, undetermined, sequelaCMS: Poisoning by otorhino drugs and prep, undetermined, sequelaCan lead a claimANone
T49.6X5 Adverse effect of otorhinolaryngological drugs and preparations
T49.6X5AAdverse effect of otorhinolaryngological drugs and preparations, initial encounterCMS: Adverse effect of otorhino drugs and preparations, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6X5DAdverse effect of otorhinolaryngological drugs and preparations, subsequent encounterCMS: Adverse effect of otorhino drugs and preparations, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6X5SAdverse effect of otorhinolaryngological drugs and preparations, sequelaCMS: Adverse effect of otorhino drugs and preparations, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6X6 Underdosing of otorhinolaryngological drugs and preparations
T49.6X6AUnderdosing of otorhinolaryngological drugs and preparations, initial encounterCMS: Underdosing of otorhino drugs and preparations, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6X6DUnderdosing of otorhinolaryngological drugs and preparations, subsequent encounterCMS: Underdosing of otorhino drugs and preparations, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.6X6SUnderdosing of otorhinolaryngological drugs and preparations, sequelaCMS: Underdosing of otorhino drugs and preparations, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7 Poisoning by, adverse effect of and underdosing of dental drugs, topically applied
T49.7X Poisoning by, adverse effect of and underdosing of dental drugs, topically applied
T49.7X1 Poisoning by dental drugs, topically applied, accidental (unintentional)
T49.7X1APoisoning by dental drugs, topically applied, accidental (unintentional), initial encounterCMS: Poisoning by dental drugs, topically applied, acc, initCan lead a claimANone
T49.7X1DPoisoning by dental drugs, topically applied, accidental (unintentional), subsequent encounterCMS: Poisoning by dental drugs, topically applied, acc, subsCan lead a claimANone
T49.7X1SPoisoning by dental drugs, topically applied, accidental (unintentional), sequelaCMS: Poisoning by dental drugs, topically applied, acc, sequelaCan lead a claimANone
T49.7X2 Poisoning by dental drugs, topically applied, intentional self-harm
T49.7X2APoisoning by dental drugs, topically applied, intentional self-harm, initial encounterCMS: Poisn by dental drugs, topically applied, self-harm, initCan lead a claimANone
T49.7X2DPoisoning by dental drugs, topically applied, intentional self-harm, subsequent encounterCMS: Poisn by dental drugs, topically applied, self-harm, subsCan lead a claimANone
T49.7X2SPoisoning by dental drugs, topically applied, intentional self-harm, sequelaCMS: Poisn by dental drugs, topically applied, self-harm, sequelaCan lead a claimANone
T49.7X3 Poisoning by dental drugs, topically applied, assault
T49.7X3APoisoning by dental drugs, topically applied, assault, initial encounterCMS: Poisoning by dental drugs, topically applied, assault, initCan lead a claimANone
T49.7X3DPoisoning by dental drugs, topically applied, assault, subsequent encounterCMS: Poisoning by dental drugs, topically applied, assault, subsCan lead a claimANone
T49.7X3SPoisoning by dental drugs, topically applied, assault, sequelaCMS: Poisn by dental drugs, topically applied, assault, sequelaCan lead a claimANone
T49.7X4 Poisoning by dental drugs, topically applied, undetermined
T49.7X4APoisoning by dental drugs, topically applied, undetermined, initial encounterCMS: Poisoning by dental drugs, topically applied, undet, initCan lead a claimANone
T49.7X4DPoisoning by dental drugs, topically applied, undetermined, subsequent encounterCMS: Poisoning by dental drugs, topically applied, undet, subsCan lead a claimANone
T49.7X4SPoisoning by dental drugs, topically applied, undetermined, sequelaCMS: Poisoning by dental drugs, topically applied, undet, sequelaCan lead a claimANone
T49.7X5 Adverse effect of dental drugs, topically applied
T49.7X5AAdverse effect of dental drugs, topically applied, initial encounterCMS: Adverse effect of dental drugs, topically applied, initCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7X5DAdverse effect of dental drugs, topically applied, subsequent encounterCMS: Adverse effect of dental drugs, topically applied, subsCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7X5SAdverse effect of dental drugs, topically applied, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7X6 Underdosing of dental drugs, topically applied
T49.7X6AUnderdosing of dental drugs, topically applied, initial encounterCMS: Underdosing of dental drugs, topically applied, init encntrCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7X6DUnderdosing of dental drugs, topically applied, subsequent encounterCMS: Underdosing of dental drugs, topically applied, subs encntrCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.7X6SUnderdosing of dental drugs, topically applied, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8 Poisoning by, adverse effect of and underdosing of other topical agents
T49.8X Poisoning by, adverse effect of and underdosing of other topical agents
T49.8X1 Poisoning by other topical agents, accidental (unintentional)
T49.8X1APoisoning by other topical agents, accidental (unintentional), initial encounterCMS: Poisoning by oth topical agents, accidental, initCan lead a claimANone
T49.8X1DPoisoning by other topical agents, accidental (unintentional), subsequent encounterCMS: Poisoning by oth topical agents, accidental, subsCan lead a claimANone
T49.8X1SPoisoning by other topical agents, accidental (unintentional), sequelaCMS: Poisoning by oth topical agents, accidental, sequelaCan lead a claimANone
T49.8X2 Poisoning by other topical agents, intentional self-harm
T49.8X2APoisoning by other topical agents, intentional self-harm, initial encounterCMS: Poisoning by oth topical agents, intentional self-harm, initCan lead a claimANone
T49.8X2DPoisoning by other topical agents, intentional self-harm, subsequent encounterCMS: Poisoning by oth topical agents, intentional self-harm, subsCan lead a claimANone
T49.8X2SPoisoning by other topical agents, intentional self-harm, sequelaCMS: Poisoning by oth topical agents, self-harm, sequelaCan lead a claimANone
T49.8X3 Poisoning by other topical agents, assault
T49.8X3APoisoning by other topical agents, assault, initial encounterCMS: Poisoning by other topical agents, assault, init encntrCan lead a claimANone
T49.8X3DPoisoning by other topical agents, assault, subsequent encounterCMS: Poisoning by other topical agents, assault, subs encntrCan lead a claimANone
T49.8X3SPoisoning by other topical agents, assault, sequelaCan lead a claimANone
T49.8X4 Poisoning by other topical agents, undetermined
T49.8X4APoisoning by other topical agents, undetermined, initial encounterCMS: Poisoning by other topical agents, undetermined, init encntrCan lead a claimANone
T49.8X4DPoisoning by other topical agents, undetermined, subsequent encounterCMS: Poisoning by other topical agents, undetermined, subs encntrCan lead a claimANone
T49.8X4SPoisoning by other topical agents, undetermined, sequelaCan lead a claimANone
T49.8X5 Adverse effect of other topical agents
T49.8X5AAdverse effect of other topical agents, initial encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8X5DAdverse effect of other topical agents, subsequent encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8X5SAdverse effect of other topical agents, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8X6 Underdosing of other topical agents
T49.8X6AUnderdosing of other topical agents, initial encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8X6DUnderdosing of other topical agents, subsequent encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.8X6SUnderdosing of other topical agents, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.9 Poisoning by, adverse effect of and underdosing of unspecified topical agent
T49.91 Poisoning by unspecified topical agent, accidental (unintentional)
T49.91XAPoisoning by unspecified topical agent, accidental (unintentional), initial encounterCMS: Poisoning by unsp topical agent, accidental, initCan lead a claimANone
T49.91XDPoisoning by unspecified topical agent, accidental (unintentional), subsequent encounterCMS: Poisoning by unsp topical agent, accidental, subsCan lead a claimANone
T49.91XSPoisoning by unspecified topical agent, accidental (unintentional), sequelaCMS: Poisoning by unsp topical agent, accidental, sequelaCan lead a claimANone
T49.92 Poisoning by unspecified topical agent, intentional self-harm
T49.92XAPoisoning by unspecified topical agent, intentional self-harm, initial encounterCMS: Poisoning by unsp topical agent, intentional self-harm, initCan lead a claimANone
T49.92XDPoisoning by unspecified topical agent, intentional self-harm, subsequent encounterCMS: Poisoning by unsp topical agent, intentional self-harm, subsCan lead a claimANone
T49.92XSPoisoning by unspecified topical agent, intentional self-harm, sequelaCMS: Poisoning by unsp topical agent, self-harm, sequelaCan lead a claimANone
T49.93 Poisoning by unspecified topical agent, assault
T49.93XAPoisoning by unspecified topical agent, assault, initial encounterCMS: Poisoning by unspecified topical agent, assault, init encntrCan lead a claimANone
T49.93XDPoisoning by unspecified topical agent, assault, subsequent encounterCMS: Poisoning by unspecified topical agent, assault, subs encntrCan lead a claimANone
T49.93XSPoisoning by unspecified topical agent, assault, sequelaCan lead a claimANone
T49.94 Poisoning by unspecified topical agent, undetermined
T49.94XAPoisoning by unspecified topical agent, undetermined, initial encounterCMS: Poisoning by unsp topical agent, undetermined, init encntrCan lead a claimANone
T49.94XDPoisoning by unspecified topical agent, undetermined, subsequent encounterCMS: Poisoning by unsp topical agent, undetermined, subs encntrCan lead a claimANone
T49.94XSPoisoning by unspecified topical agent, undetermined, sequelaCMS: Poisoning by unsp topical agent, undetermined, sequelaCan lead a claimANone
T49.95 Adverse effect of unspecified topical agent
T49.95XAAdverse effect of unspecified topical agent, initial encounterCMS: Adverse effect of unspecified topical agent, init encntrCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.95XDAdverse effect of unspecified topical agent, subsequent encounterCMS: Adverse effect of unspecified topical agent, subs encntrCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.95XSAdverse effect of unspecified topical agent, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.96 Underdosing of unspecified topical agent
T49.96XAUnderdosing of unspecified topical agent, initial encounterCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.96XDUnderdosing of unspecified topical agent, subsequent encounterCMS: Underdosing of unspecified topical agent, subs encntrCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone
T49.96XSUnderdosing of unspecified topical agent, sequelaCannot lead a claimUnacceptable principal diagnosis, code is not reportable as principal diagnosisNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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