October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

R78 Findings of drugs and other substances, not normally found in blood

All 13 codes in the R78 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

13

Can lead a claim

0

Cannot lead a claim

13

What CMS assigns to R78

None of the 13 codes is assigned a clinical group. None of the 13 is assigned a comorbidity subgroup. None can lead a claim.

Every code in R78

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
R78.0Finding of alcohol in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.1Finding of opiate drug in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.2Finding of cocaine in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.3Finding of hallucinogen in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.4Finding of other drugs of addictive potential in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.5Finding of other psychotropic drug in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.6Finding of steroid agent in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.7 Finding of abnormal level of heavy metals in blood
R78.71Abnormal lead level in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.72Abnormal gadolinium level in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.79Finding of abnormal level of heavy metals in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.8 Finding of other specified substances, not normally found in blood
R78.81BacteremiaCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.89Finding of other specified substances, not normally found in bloodCMS: Finding of oth substances, not normally found in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
R78.9Finding of unspecified substance, not normally found in bloodCMS: Finding of unsp substance, not normally found in bloodCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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