October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

P04 Newborn affected by noxious substances transmitted via placenta or breast milk

All 22 codes in the P04 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

22

Can lead a claim

10

Cannot lead a claim

12

What CMS assigns to P04

10 of the 22 codes group to MMTA - Other; 12 are assigned no clinical group. None of the 22 is assigned a comorbidity subgroup. 10 of the 22 can lead a claim. CMS attaches a code-first note to all 22.

Code first

CMS grouper convention 12, on P04.0, P04.2, P04.3, P04.40, P04.41, P04.42, P04.49, P04.5, P04.6, P04.81, P04.89, P04.9. Code first:

  • underlying disease

CMS grouper convention 148, on P04.11, P04.12, P04.13, P04.14, P04.15, P04.16, P04.17, P04.1A, P04.18, P04.19. Code first:

  • , if applicable, withdrawal symptoms from maternal use of drugs of addiction (P96.1)
  • any current condition in newborn, if applicable
  • withdrawal symptoms from therapeutic use of drugs in newborn (P96.2)

Every code in P04

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
P04.0Newborn affected by maternal anesthesia and analgesia in pregnancy, labor and deliveryCMS: NB aff by matern anesth and analgesia in preg, labor and delCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.1 Newborn affected by other maternal medication
P04.11Newborn affected by maternal antineoplastic chemotherapyCan lead a claim, code first appliesANone
P04.12Newborn affected by maternal cytotoxic drugsCan lead a claim, code first appliesANone
P04.13Newborn affected by maternal use of anticonvulsantsCan lead a claim, code first appliesANone
P04.14Newborn affected by maternal use of opiatesCan lead a claim, code first appliesANone
P04.15Newborn affected by maternal use of antidepressantsCan lead a claim, code first appliesANone
P04.16Newborn affected by maternal use of amphetaminesCan lead a claim, code first appliesANone
P04.17Newborn affected by maternal use of sedative-hypnoticsCan lead a claim, code first appliesANone
P04.1ANewborn affected by maternal use of anxiolyticsCan lead a claim, code first appliesANone
P04.18Newborn affected by other maternal medicationCan lead a claim, code first appliesANone
P04.19Newborn affected by maternal use of unspecified medicationCan lead a claim, code first appliesANone
P04.2Newborn affected by maternal use of tobaccoCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.3Newborn affected by maternal use of alcoholCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.4 Newborn affected by maternal use of drugs of addiction
P04.40Newborn affected by maternal use of unspecified drugs of addictionCMS: Newborn affected by maternal use of unsp drugs of addictionCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.41Newborn affected by maternal use of cocaineCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.42Newborn affected by maternal use of hallucinogensCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.49Newborn affected by maternal use of other drugs of addictionCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.5Newborn affected by maternal use of nutritional chemical substancesCMS: Newborn aff by maternal use of nutritional chemical substncCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.6Newborn affected by maternal exposure to environmental chemical substancesCMS: Newborn aff by maternal exposure to environ chemical substncCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.8 Newborn affected by other maternal noxious substances
P04.81Newborn affected by maternal use of cannabisCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.89Newborn affected by other maternal noxious substancesCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone
P04.9Newborn affected by maternal noxious substance, unspecifiedCannot lead a claimPrincipal diagnosis not assigned to a clinical groupNoneNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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