ICD-10 · PDGM grouping
E21 Hyperparathyroidism and other disorders of parathyroid gland
All 6 codes in the E21 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
6
Can lead a claim
5
Cannot lead a claim
1
What CMS assigns to E21
5 of the 6 codes group to MMTA - Endocrine; 1 is assigned no clinical group. None of the 6 is assigned a comorbidity subgroup. 5 of the 6 can lead a claim.
Every code in E21
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| E21.0 | Primary hyperparathyroidism | Can lead a claim | I | None |
| E21.1 | Secondary hyperparathyroidism, not elsewhere classified | Can lead a claim | I | None |
| E21.2 | Other hyperparathyroidism | Can lead a claim | I | None |
| E21.3 | Hyperparathyroidism, unspecified | Can lead a claim | I | None |
| E21.4 | Other specified disorders of parathyroid gland | Can lead a claim | I | None |
| E21.5 | Disorder of parathyroid gland, unspecified | Cannot lead a claimPrincipal diagnosis not assigned to a clinical group | None | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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