October 1 update. Our PDGM and ICD-10 tools now use the FY2027 code set: 190 codes added, 30 deleted, and no existing code changed clinical group.

See what changed

ICD-10 · PDGM grouping

D46 Myelodysplastic syndromes

All 11 codes in the D46 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.

ICD-10-CM FY2027 · CMS grouper v07.2.26

Codes in family

11

Can lead a claim

11

Cannot lead a claim

0

What CMS assigns to D46

All 11 codes group to MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases. None of the 11 is assigned a comorbidity subgroup. Every code can lead a claim.

Every code in D46

Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.

CodeDescriptionPrimary positionClinical groupComorbidity subgroup
D46.0Refractory anemia without ring sideroblasts, so statedCan lead a claimKNone
D46.1Refractory anemia with ring sideroblastsCan lead a claimKNone
D46.2 Refractory anemia with excess of blasts [RAEB]
D46.20Refractory anemia with excess of blasts, unspecifiedCan lead a claimKNone
D46.21Refractory anemia with excess of blasts 1Can lead a claimKNone
D46.22Refractory anemia with excess of blasts 2Can lead a claimKNone
D46.ARefractory cytopenia with multilineage dysplasiaCan lead a claimKNone
D46.BRefractory cytopenia with multilineage dysplasia and ring sideroblastsCMS: Refract cytopenia w multilin dysplasia and ring sideroblastsCan lead a claimKNone
D46.CMyelodysplastic syndrome with isolated del(5q) chromosomal abnormalityCMS: Myelodysplastic syndrome w isolated del(5q) chromsoml abnltCan lead a claimKNone
D46.4Refractory anemia, unspecifiedCan lead a claimKNone
D46.ZOther myelodysplastic syndromesCan lead a claimKNone
D46.9Myelodysplastic syndrome, unspecifiedCan lead a claimKNone

Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.

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