ICD-10 · PDGM grouping
A81 Atypical virus infections of central nervous system
All 10 codes in the A81 family, with the PDGM clinical group, comorbidity subgroup and primary-position rule CMS assigns, read from the CMS grouper crosswalk v07.2.26 and the CDC FY2027 code file.
Codes in family
10
Can lead a claim
10
Cannot lead a claim
0
What CMS assigns to A81
All 10 codes group to Neuro Rehabilitation. None of the 10 is assigned a comorbidity subgroup. Every code can lead a claim.
Every code in A81
Descriptions are CDC’s FY2027 wording; where CMS’s grouper abbreviates one, its form is shown beneath.
| Code | Description | Primary position | Clinical group | Comorbidity subgroup |
|---|---|---|---|---|
| A81.0 Creutzfeldt-Jakob disease | ||||
| A81.00 | Creutzfeldt-Jakob disease, unspecified | Can lead a claim | B | None |
| A81.01 | Variant Creutzfeldt-Jakob disease | Can lead a claim | B | None |
| A81.09 | Other Creutzfeldt-Jakob disease | Can lead a claim | B | None |
| A81.1 | Subacute sclerosing panencephalitis | Can lead a claim | B | None |
| A81.2 | Progressive multifocal leukoencephalopathy | Can lead a claim | B | None |
| A81.8 Other atypical virus infections of central nervous system | ||||
| A81.81 | Kuru | Can lead a claim | B | None |
| A81.82 | Gerstmann-Straussler-Scheinker syndrome | Can lead a claim | B | None |
| A81.83 | Fatal familial insomnia | Can lead a claim | B | None |
| A81.89 | Other atypical virus infections of central nervous system | Can lead a claim | B | None |
| A81.9 | Atypical virus infection of central nervous system, unspecifiedCMS: Atypical virus infection of central nervous system, unsp | Can lead a claim | B | None |
Sources: CMS HH PPS Grouper Software v07.2.26, effective 2026-10-01, for the clinical group, comorbidity subgroup, code-first conventions and primary-position flags; CDC NCHS ICD-10-CM FY2027 code descriptions for the family title and code wording. This is the crosswalk Medicare runs a claim through. Grouping also depends on admission source, timing, the OASIS functional items and the rest of the diagnosis list.
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